| Sku |
AAP38431 |
| Old sku |
AAPP20620 |
| Price |
$99.00 |
| Name |
COPS2 Peptide (AAP38431) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
COPS2 |
| Alias symbols |
ALIEN, CSN2, SGN2, TRIP15 |
| Gene id |
9318 |
| Description of target |
COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1. |
| Swissprot id |
P61203 |
| Protein accession num |
NP_004227 |
| Nucleotide accession num |
NM_004236 |
| Protein size |
443 amino acids |
| Molecular weight |
51kDa |
| Application |
IHC, WB |
| Partner proteins |
COPS2,COPS4,COPS6,GPS1,COPS2,COPS3,COPS4,COPS5,COPS6,COPS7A,COPS8,CUL5,GFER,GPS1,IRF8,MAPK8,NIF3L1,NR0B1,NR2F1,RARA,RXRA,THRA,THRB,TP53,COPS5,COPS6,COPS8,CPSF1,CUL4A,DDB1,EcR,IRF8,KLHL13,NIF3L1,NR0B1,NR2F1,SIN3A,Sin3a,THRA,THRB,Thrb,UIMC1,WDR8 |
| Subunit |
2 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Moehren,U., (2004) (er) Nucleic Acids Res. 32 (10), 2995-3004 |
| Description |
This is a synthetic peptide designed for use in combination with anti-COPS2 antibody (Catalog #: ARP38431_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
