HMGA2 Peptide (AAP38356)

Data Sheet
 
Sku AAP38356
Old sku AAPP20543
Price $99.00
Name HMGA2 Peptide (AAP38356)
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Size 100 ug
Gene HMGA2
Alias symbols BABL, HMGI-C, HMGIC, LIPO, STQTL9
Gene id 8091
Description of target HMGA2 belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. It may be play a role in adipogenesis, mesenchymal differentiation and diet-induced obesity.This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Swissprot id P52926
Protein accession num NP_003474
Nucleotide accession num NM_003483
Protein size 109 amino acids
Molecular weight 12kDa
Application WB
Partner proteins CDK1,CSNK2A1,CSNK2A2,NFKB1,PIAS3,RELA,SMAD3,NFKB1,PIAS3,RELA
Quality control The peptide is characterized by mass spectroscopy
Key reference Kubo,T., (2006) Biochem. Biophys. Res. Commun. 340 (2), 476-481
Description This is a synthetic peptide designed for use in combination with anti-HMGA2 antibody (Catalog #: ARP38356_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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