| Sku |
AAP38257 |
| Old sku |
AAPP23111 |
| Price |
$99.00 |
| Name |
STAT6 Peptide (AAP38257) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
STAT6 |
| Alias symbols |
D12S1644, IL-4-STAT, STAT6B, STAT6C |
| Gene id |
6778 |
| Description of target |
STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. |
| Swissprot id |
P42226 |
| Protein accession num |
NP_003144 |
| Nucleotide accession num |
NM_003153 |
| Protein size |
847 amino acids |
| Molecular weight |
94kDa |
| Application |
IHC, WB |
| Partner proteins |
IL4R,NMI,STAT6,CEBPB,CREBBP,EP300,ETS1,HIST2H3C,IL4R,IRF4,JAK1,NCOA1,NFKB1,NMI,PRKCZ,PTPN6,RELA,SND1,SRC,STAT2,STAT6,ANXA2,CREBBP,EP300,IRF4,NCOA1,NFKB1,SND1,TP53 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Blanchard,C., (2005) Int. J. Biochem. Cell Biol. 37 (12), 2559-2573 |
| Description |
This is a synthetic peptide designed for use in combination with anti-STAT6 antibody (Catalog #: ARP38257_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
