| Sku |
AAP38089 |
| Old sku |
AAPP20263 |
| Price |
$99.00 |
| Name |
E2F3 Peptide (AAP38089) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
E2F3 |
| Alias symbols |
E2F-3 |
| Gene id |
1871 |
| Description of target |
E2F3 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. E2F3 binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner. |
| Swissprot id |
Q68DT0 |
| Protein accession num |
CAH18140 |
| Nucleotide accession num |
NM_001243076 |
| Protein size |
334 amino acids |
| Molecular weight |
37kDa |
| Application |
WB |
| Partner proteins |
BIRC5,CDC25A,CDC6,CDK1,EAPP,FHL2,GAB2,JMY,MSH2,MT1G,MYBL2,PPP1R13B,RYBP,TP53BP2,TP53INP1,UXT,CCNA2,CDK3,RB1,RYBP,SP1,TFDP1,TFDP2,TFE3,YY1,CREBBP,FHL2,MGA,MYBL2,PKIB,RNF144A,RYBP,SPIB,Sp1,TEAD3,TFE3,WNK1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Koehrer,K., et al., (2004) The German cDNA Consortium |
| Description |
This is a synthetic peptide designed for use in combination with anti-E2F3 antibody (Catalog #: ARP38089_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
