ATF4 Peptide (AAP38067)

Data Sheet
 
Sku AAP38067
Old sku AAPP20241
Price $99.00
Name ATF4 Peptide (AAP38067)
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Size 100 ug
Gene ATF4
Alias symbols CREB2, TXREB, CREB-2, TAXREB67
Gene id 468
Description of target ATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Swissprot id P18848
Protein accession num NP_001666
Nucleotide accession num NM_001675
Protein size 351 amino acids
Molecular weight 39kDa
Application WB
Partner proteins DISC1,DISC1,TRIB3,CCDC106,CEBPB,CEBPG,CREBZF,DAPK3,DDIT3,DISC1,GABBR2,GPS2,GTF2F2,JUN,LDOC1,NFE2L1,NFE2L2,POLR2C,PTCD3,TREX2,TRIB3,TTR,ATF3,CCDC106,CREBBP,Cebpb,DISC1,EIF2A,GABBR1,GABBR2,GPS2,GTF2B,GTF2F2,JUN,LDOC1,POLR2C,PTCD3,TBP,TREX2,TRIB3,TTR
Quality control The peptide is characterized by mass spectroscopy
Key reference Lassot,I., et al., (2005) J. Biol. Chem. 280 (50), 41537-41545
Description This is a synthetic peptide designed for use in combination with anti-ATF4 antibody (Catalog #: ARP38067_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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