Sku |
AAP38067 |
Old sku |
AAPP20241 |
Price |
$99.00 |
Name |
ATF4 Peptide (AAP38067) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
ATF4 |
Alias symbols |
CREB2, TXREB, CREB-2, TAXREB67 |
Gene id |
468 |
Description of target |
ATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. |
Swissprot id |
P18848 |
Protein accession num |
NP_001666 |
Nucleotide accession num |
NM_001675 |
Protein size |
351 amino acids |
Molecular weight |
39kDa |
Application |
WB |
Partner proteins |
DISC1,DISC1,TRIB3,CCDC106,CEBPB,CEBPG,CREBZF,DAPK3,DDIT3,DISC1,GABBR2,GPS2,GTF2F2,JUN,LDOC1,NFE2L1,NFE2L2,POLR2C,PTCD3,TREX2,TRIB3,TTR,ATF3,CCDC106,CREBBP,Cebpb,DISC1,EIF2A,GABBR1,GABBR2,GPS2,GTF2B,GTF2F2,JUN,LDOC1,POLR2C,PTCD3,TBP,TREX2,TRIB3,TTR |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Lassot,I., et al., (2005) J. Biol. Chem. 280 (50), 41537-41545 |
Description |
This is a synthetic peptide designed for use in combination with anti-ATF4 antibody (Catalog #: ARP38067_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |