ID4 Peptide (AAP38058)

Data Sheet
 
Sku AAP38058
Old sku AAPP20232
Price $99.00
Name ID4 Peptide (AAP38058)
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Size 100 ug
Gene ID4
Alias symbols IDB4, bHLHb27
Gene id 3400
Description of target Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995).[supplied by OMIM].
Swissprot id P47928
Protein accession num NP_001537
Nucleotide accession num NM_001546
Protein size 161 amino acids
Molecular weight 17kDa
Application WB
Partner proteins HES1,ID3,MYOD1,TCF4
Quality control The peptide is characterized by mass spectroscopy
Key reference Yu,L., et al., (2005) Nat. Genet. 37 (3), 265-274
Description This is a synthetic peptide designed for use in combination with anti-ID4 antibody (Catalog #: ARP38058_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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