Sku |
AAP38058 |
Old sku |
AAPP20232 |
Price |
$99.00 |
Name |
ID4 Peptide (AAP38058) |
Purchase info |
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|
Size |
100 ug |
Gene |
ID4 |
Alias symbols |
IDB4, bHLHb27 |
Gene id |
3400 |
Description of target |
Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995).[supplied by OMIM]. |
Swissprot id |
P47928 |
Protein accession num |
NP_001537 |
Nucleotide accession num |
NM_001546 |
Protein size |
161 amino acids |
Molecular weight |
17kDa |
Application |
WB |
Partner proteins |
HES1,ID3,MYOD1,TCF4 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Yu,L., et al., (2005) Nat. Genet. 37 (3), 265-274 |
Description |
This is a synthetic peptide designed for use in combination with anti-ID4 antibody (Catalog #: ARP38058_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |