KCNAB2 Peptide (AAP37678)

Data Sheet
 
Sku AAP37678
Old sku AAPP09012
Price $99.00
Name KCNAB2 Peptide (AAP37678)
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Size 100 ug
Gene KCNAB2
Alias symbols AKR6A5, KCNA2B, HKvbeta2, KV-BETA-2, HKvbeta2.1, HKvbeta2.2
Gene id 8514
Description of target This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
Swissprot id Q13303
Protein accession num NP_003627
Nucleotide accession num NM_003636
Protein size 367 amino acids
Molecular weight 40kDa
Application IHC, WB
Partner proteins ATXN1,CD4,KCNA2,SLC39A1,SLC39A2,SQSTM1,CD4,KCNA2
Subunit beta-2
Quality control The peptide is characterized by mass spectroscopy
Key reference Gu,C., et al., (2003) Science 301 (5633), 646-649
Description This is a synthetic peptide designed for use in combination with anti-KCNAB2 antibody (Catalog #: ARP37678_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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