Foxa2 Peptide - middle region (AAP37060)

Data Sheet
 
Sku AAP37060
Old sku AAPP09254
Price $99.00
Name Foxa2 Peptide - middle region (AAP37060)
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Size 100ug
Gene Foxa2
Alias symbols HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b
Gene id 15376
Description of target Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs.
Swissprot id P35583
Protein accession num NP_034576
Nucleotide accession num NM_010446
Protein size 459 amino acids
Molecular weight 48kDa
Species reactivity Mouse
Application WB
Peptide sequence SSGGKKTAPGSQASQAQLGEAAGSASETPAGTESPHSSASPCQEHKRGGL
Partner proteins Acadm,Acadvl,Gck,Hnf4a,Igfbp1,Pklr,Ucp2
Quality control The peptide is characterized by mass spectroscopy
Key reference N/A
Description This is a synthetic peptide designed for use in combination with anti-Foxa2 Antibody(ARP37060_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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