Sku |
AAP37060 |
Old sku |
AAPP09254 |
Price |
$99.00 |
Name |
Foxa2 Peptide - middle region (AAP37060) |
Purchase info |
To purchase this peptide:
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|
Size |
100ug |
Gene |
Foxa2 |
Alias symbols |
HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b |
Gene id |
15376 |
Description of target |
Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs. |
Swissprot id |
P35583 |
Protein accession num |
NP_034576 |
Nucleotide accession num |
NM_010446 |
Protein size |
459 amino acids |
Molecular weight |
48kDa |
Species reactivity |
Mouse |
Application |
WB |
Peptide sequence |
SSGGKKTAPGSQASQAQLGEAAGSASETPAGTESPHSSASPCQEHKRGGL |
Partner proteins |
Acadm,Acadvl,Gck,Hnf4a,Igfbp1,Pklr,Ucp2 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
N/A |
Description |
This is a synthetic peptide designed for use in combination with anti-Foxa2 Antibody(ARP37060_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |