| Sku |
AAP36647 |
| Old sku |
AAPP07904 |
| Price |
$99.00 |
| Name |
MCM2 Peptide (AAP36647) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
MCM2 |
| Alias symbols |
BM28, CCNL1, CDCL1, cdc19, D3S3194, MITOTIN |
| Gene id |
4171 |
| Description of target |
The protein encoded by MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. |
| Swissprot id |
P49736 |
| Protein accession num |
NP_004517 |
| Nucleotide accession num |
NM_004526 |
| Protein size |
904 amino acids |
| Molecular weight |
99kDa |
| Application |
WB |
| Partner proteins |
MCM3,MCM3,MCM5,MCM5,MCM6,MCM6,AKAP8,CCNB2,CDC6,CDC7,CDK4,CDK6,CDKN2A,CPSF1,DBF4,GNB5,GTF2B,GTF2H1,HIST3H3,MCM10,MCM2,MCM3,MCM4,MCM5,MCM6,MCM7,MOBKL3,MPP3,MYST2,ORC1L,ORC2L,ORC4L,ORC5L,ORC6L,PHC2,PLK1,RAD52,RPA1,RPA2,RPA3,RPS4X,TBP,AIRE,AKAP8,ATM,ATR,BRCC3,CCNC,CDC7,DBF4,GNB5,ING5,MCM2,MCM3,MCM4,MCM5,MCM6,MCM7,MOBKL3,MPP3,ORC1L,ORC2L,ORC4L,ORC5L,PHC2,RPA1,RPA2,RPA3,RPS4X,TBP,TCEA2 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Yu,Z., et al., (2004) J. Mol. Biol. 340 (5), 1197-1206 |
| Description |
This is a synthetic peptide designed for use in combination with anti-MCM2 antibody (Catalog #: ARP36647_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
|
