GJB2 Peptide (AAP36608)

Data Sheet
 
Sku AAP36608
Old sku AAPP07847
Price $99.00
Name GJB2 Peptide (AAP36608)
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Size 100 ug
Gene GJB2
Alias symbols HID, KID, PPK, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A
Gene id 2706
Description of target Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1; MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.
Swissprot id P29033
Protein accession num NP_003995
Nucleotide accession num NM_004004
Protein size 226 amino acids
Molecular weight 25kDa
Application WB
Partner proteins CAV1,GJB1,GJB6,CAV1
Quality control The peptide is characterized by mass spectroscopy
Key reference Hromas,R., et al., (2004) Neurosci. Res. 50 (1), 125-128
Description This is a synthetic peptide designed for use in combination with anti-GJB2 antibody (Catalog #: ARP36608_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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