RAD54B Peptide - middle region (AAP36408)

Data Sheet
 
Sku AAP36408
Old sku AAPP08464
Price $99.00
Name RAD54B Peptide - middle region (AAP36408)
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Size 100 ug
Gene RAD54B
Alias symbols FSBP, RDH54
Gene id 25788
Description of target RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
Swissprot id Q9Y620
Protein accession num NP_036547
Nucleotide accession num NM_012415
Protein size 910 amino acids
Molecular weight 103kDa
Application IHC, WB
Partner proteins DMC1,CCDC33,CDC23,CSNK1E,DMC1,DYRK2,GORASP2,LNX1,PSMA1,RAD51,RAD54B,RIBC2,TRAPPC6A,UBE2I,ZNF580,CCDC33,CD2BP2,CDC23,CSNK1E,DYRK2,GORASP2,LNX1,MYO15B,PSMA1,RAD51,RAD54B,RIBC2,TCEANC,TRAPPC6A,UBE2I,ZNF580
Quality control The peptide is characterized by mass spectroscopy
Key reference Brys,M., (2007) Pol J Pathol 58 (1), 3-6
Description This is a synthetic peptide designed for use in combination with anti-RAD54B antibody (Catalog #: ARP36408_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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