MAGEA9 Peptide - middle region (AAP35768)

Data Sheet
 
Sku AAP35768
Old sku AAPP07020
Price $99.00
Name MAGEA9 Peptide - middle region (AAP35768)
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Size 100 ug
Gene MAGEA9
Alias symbols MAGE9, MGC8421, CT1.9, MAGEA9B
Gene id 4108
Description of target MAGEA9 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This pseudogene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. It is possible that, in rare cases, a combination of two SNPs in this gene may result in an open reading frame encoding a functional enzyme which metabolizes codeine to morphine. This locus is part of a cluster of cytochrome P450 genes on chromosome 22q13.1. This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Swissprot id P43362
Protein accession num NP_005356
Nucleotide accession num NM_005365
Protein size 315 amino acids
Molecular weight 35kDa
Application WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Oehlrich,N., (2005) Int. J. Cancer 117 (2), 256-264
Description This is a synthetic peptide designed for use in combination with anti-MAGEA9 antibody (Catalog #: ARP35768_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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