PITX2 Peptide (AAP35634)

Data Sheet
 
Sku AAP35634
Old sku AAPP07881
Price $99.00
Name PITX2 Peptide (AAP35634)
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Size 100 ug
Gene PITX2
Alias symbols RS, RGS, ARP1, Brx1, IDG2, IGDS, IHG2, PTX2, RIEG, IGDS2, IRID2, Otlx2, RIEG1
Gene id 5308
Description of target The PITX2 gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. Mutations in PITX2 are associated with Axenfeld-Rieger syndrome (ARS), iridogoniodysgenesis syndrome (IGDS), and sporadic cases of Peters anomaly. This protein is involved in the development of the eye, tooth and abdominal organs. It also acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
Swissprot id Q99697-2
Protein accession num NP_000316
Nucleotide accession num NM_000325
Protein size 324 amino acids
Molecular weight 36kDa
Application IHC, WB
Partner proteins CTNNB1,HDAC1,KAT5,LEF1,PDLIM1,PITX2,PROP1,HERC5,MSX2,PITX2,Pou1f1,TRIM25
Quality control The peptide is characterized by mass spectroscopy
Key reference Martin,D.M., et al., (2004) Dev. Biol. 267 (1), 93-108
Description This is a synthetic peptide designed for use in combination with anti-PITX2 antibody (Catalog #: ARP35634_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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