TRPC6 Peptide - middle region (AAP35144)

Data Sheet
 
Sku AAP35144
Old sku AAPP08603
Price $99.00
Name TRPC6 Peptide - middle region (AAP35144)
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Size 100 ug
Gene TRPC6
Alias symbols FLJ11098, FLJ14863, FSGS2, TRP6
Gene id 7225
Description of target TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Swissprot id Q9Y210
Protein accession num NP_004612
Nucleotide accession num NM_004621
Protein size 931 amino acids
Molecular weight 106kDa
Application WB
Partner proteins MX1,FYN,ITPR3,MX1,ORAI1,SRC,TRPC3,TRPC6,TRPM2,FYN,ITPR1,ITPR3,SRC,TRPC1,TRPC2,TRPC3,TRPC4,TRPC5,TRPC6,TRPC7
Quality control The peptide is characterized by mass spectroscopy
Key reference Liu,D., (2008) Arterioscler. Thromb. Vasc. Biol. 28 (4), 746-751
Description This is a synthetic peptide designed for use in combination with anti-TRPC6 antibody (Catalog #: ARP35144_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
Protocol
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