Sku |
AAP35144 |
Old sku |
AAPP08603 |
Price |
$99.00 |
Name |
TRPC6 Peptide - middle region (AAP35144) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
TRPC6 |
Alias symbols |
FLJ11098, FLJ14863, FSGS2, TRP6 |
Gene id |
7225 |
Description of target |
TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). |
Swissprot id |
Q9Y210 |
Protein accession num |
NP_004612 |
Nucleotide accession num |
NM_004621 |
Protein size |
931 amino acids |
Molecular weight |
106kDa |
Application |
WB |
Partner proteins |
MX1,FYN,ITPR3,MX1,ORAI1,SRC,TRPC3,TRPC6,TRPM2,FYN,ITPR1,ITPR3,SRC,TRPC1,TRPC2,TRPC3,TRPC4,TRPC5,TRPC6,TRPC7 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Liu,D., (2008) Arterioscler. Thromb. Vasc. Biol. 28 (4), 746-751 |
Description |
This is a synthetic peptide designed for use in combination with anti-TRPC6 antibody (Catalog #: ARP35144_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |