KCNN3 Peptide (AAP35097)

Data Sheet
 
Sku AAP35097
Old sku AAPP06328
Price $99.00
Name KCNN3 Peptide (AAP35097)
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Size 100 ug
Gene KCNN3
Alias symbols SK3, hSK3, SKCA3, KCa2.3
Gene id 3782
Description of target Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
Swissprot id Q9UGI6
Protein accession num NP_002240
Nucleotide accession num NM_002249
Protein size 736 amino acids
Molecular weight 81kDa
Application IHC, WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Kolski-Andreaco,A., et al., (2004) J. Biol. Chem. 279 (8), 6893-6904
Description This is a synthetic peptide designed for use in combination with anti-KCNN3 antibody (Catalog #: ARP35097_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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