SCN5A Peptide - N-terminal region (AAP34934)

Data Sheet
 
Sku AAP34934
Old sku AAPP06157
Price $99.00
Name SCN5A Peptide - N-terminal region (AAP34934)
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Size 100 ug
Gene SCN5A
Alias symbols CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Gene id 6331
Description of target SCN5A is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. The protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.
Swissprot id Q14524
Protein accession num NP_000326
Nucleotide accession num NM_000335
Protein size 2015 amino acids
Molecular weight 227kDa
Application WB
Partner proteins CBL,DLG1,DLG2,DLG3,DLG4,INADL,NEDD4L,RGS2,RGS3,SCN5A,SNTA1,SNTB1,SNTB2,SNTG2,SNTA1,SNTB1,SNTB2
Subunit alpha
Quality control The peptide is characterized by mass spectroscopy
Key reference Van (2008) Heart Rhythm 5 (5), 712-715
Description This is a synthetic peptide designed for use in combination with anti-SCN5A antibody (Catalog #: ARP34934_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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