Sku |
AAP34934 |
Old sku |
AAPP06157 |
Price |
$99.00 |
Name |
SCN5A Peptide - N-terminal region (AAP34934) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
SCN5A |
Alias symbols |
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1 |
Gene id |
6331 |
Description of target |
SCN5A is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. The protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. |
Swissprot id |
Q14524 |
Protein accession num |
NP_000326 |
Nucleotide accession num |
NM_000335 |
Protein size |
2015 amino acids |
Molecular weight |
227kDa |
Application |
WB |
Partner proteins |
CBL,DLG1,DLG2,DLG3,DLG4,INADL,NEDD4L,RGS2,RGS3,SCN5A,SNTA1,SNTB1,SNTB2,SNTG2,SNTA1,SNTB1,SNTB2 |
Subunit |
alpha |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Van (2008) Heart Rhythm 5 (5), 712-715 |
Description |
This is a synthetic peptide designed for use in combination with anti-SCN5A antibody (Catalog #: ARP34934_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |