AMOT Peptide - N-terminal region (AAP34661)

Data Sheet
 
Sku AAP34661
Old sku AAPP23628
Price $99.00
Name AMOT Peptide - N-terminal region (AAP34661)
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Size 100 ug
Gene AMOT
Alias symbols KIAA1071
Gene id 154796
Description of target AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
Swissprot id Q4VCS5
Protein accession num NP_573572
Nucleotide accession num NM_133265
Protein size 675 amino acids
Molecular weight 72kDa
Application WB
Partner proteins MAGI1,PLG,AMOTL1,BAG3,DLG1,DYNLL1,DYNLL2,FOXK1,FOXK2,LIN7A,LIN7C,LONP2,MLH1,MPDZ,MPP5,MPP7,NEDD4L,NF2,NIN,SCLT1,UIMC1,USP11,USP42,YAP1
Quality control The peptide is characterized by mass spectroscopy
Key reference Holmgren,L., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (24), 9208-9213
Description This is a synthetic peptide designed for use in combination with anti-AMOT antibody (Catalog #: ARP34661_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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