Sku |
AAP34660 |
Old sku |
AAPP05850 |
Price |
$99.00 |
Name |
AMOT Peptide - N-terminal region (AAP34660) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
AMOT |
Alias symbols |
KIAA1071 |
Gene id |
154796 |
Description of target |
AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Swissprot id |
Q4VCS5 |
Protein accession num |
NP_573572 |
Nucleotide accession num |
NM_133265 |
Protein size |
675 amino acids |
Molecular weight |
73kDa |
Application |
WB |
Partner proteins |
MAGI1,PLG,AMOTL1,BAG3,DLG1,DYNLL1,DYNLL2,FOXK1,FOXK2,LIN7A,LIN7C,LONP2,MLH1,MPDZ,MPP5,MPP7,NEDD4L,NF2,NIN,SCLT1,UIMC1,USP11,USP42,YAP1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Holmgren,L., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (24), 9208-9213 |
Description |
This is a synthetic peptide designed for use in combination with anti-AMOT antibody (Catalog #: ARP34660_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |