Sku |
AAP34220 |
Old sku |
AAPP05535 |
Price |
$99.00 |
Name |
MED6 Peptide - middle region (AAP34220) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
MED6 |
Alias symbols |
NY-REN-28 |
Gene id |
10001 |
Description of target |
MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Swissprot id |
O75586 |
Protein accession num |
NP_005457 |
Nucleotide accession num |
NM_005466 |
Protein size |
246 amino acids |
Molecular weight |
28kDa |
Application |
WB, CHIP |
Partner proteins |
PARP1,RARA,MED25,MED8,MED9,PARP1,RARA,SMAD1,SMAD2,CDK8,ESR1,ESR2,MED1,MED10,MED14,MED15,MED19,MED21,MED25,MED26,MED28,MED29,MED30,MED9,THRA,VDR |
Subunit |
6 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Pavri,R., (2005) Mol. Cell 18 (1), 83-96 |
Description |
This is a synthetic peptide designed for use in combination with anti-MED6 antibody (Catalog #: ARP34220_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |