Sku |
AAP34192 |
Old sku |
AAPP05507 |
Price |
$99.00 |
Name |
CRSP6 Peptide - N-terminal region (AAP34192) |
Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
Size |
100 ug |
Gene |
MED17 |
Alias symbols |
CRSP6, CRSP77, DRIP80, TRAP80 |
Gene id |
9440 |
Description of target |
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. |
Swissprot id |
Q9NVC6 |
Protein accession num |
NP_004259 |
Nucleotide accession num |
NM_004268 |
Protein size |
651 amino acids |
Molecular weight |
73kDa |
Application |
IHC, WB, CHIP |
Partner proteins |
UBC; BRCA1; CDK19; CDK8; MED26; POLR2C; ESR2; MED19; FBXW7; EPAS1; TFIP11; MED24; MED21; MED14; MED11; MED28; WDR33; CPSF2; UBD; BCL6; SMARCA4; SUZ12; MED10; CTDP1; SREBF1; MED25; MED15; TRA; MED1; OBFC1; MED18; ZC3H13; MED12; QKI; TRIP4; TADA2A; SUPT7L; |
Subunit |
17 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Wang,Q., et al., (2002) J. Biol. Chem. 277 (45), 42852-42858 |
Description |
This is a synthetic peptide designed for use in combination with anti-CRSP6 antibody (Catalog #: ARP34192_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |