CRSP6 Peptide - N-terminal region (AAP34192)

Data Sheet
 
Sku AAP34192
Old sku AAPP05507
Price $99.00
Name CRSP6 Peptide - N-terminal region (AAP34192)
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Size 100 ug
Gene MED17
Alias symbols CRSP6, CRSP77, DRIP80, TRAP80
Gene id 9440
Description of target The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Swissprot id Q9NVC6
Protein accession num NP_004259
Nucleotide accession num NM_004268
Protein size 651 amino acids
Molecular weight 73kDa
Application IHC, WB, CHIP
Partner proteins UBC; BRCA1; CDK19; CDK8; MED26; POLR2C; ESR2; MED19; FBXW7; EPAS1; TFIP11; MED24; MED21; MED14; MED11; MED28; WDR33; CPSF2; UBD; BCL6; SMARCA4; SUZ12; MED10; CTDP1; SREBF1; MED25; MED15; TRA; MED1; OBFC1; MED18; ZC3H13; MED12; QKI; TRIP4; TADA2A; SUPT7L;
Subunit 17
Quality control The peptide is characterized by mass spectroscopy
Key reference Wang,Q., et al., (2002) J. Biol. Chem. 277 (45), 42852-42858
Description This is a synthetic peptide designed for use in combination with anti-CRSP6 antibody (Catalog #: ARP34192_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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