| Sku |
AAP33840 |
| Old sku |
AAPP04911 |
| Price |
$99.00 |
| Name |
SLC1A2 Peptide - N-terminal region (AAP33840) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
SLC1A2 |
| Alias symbols |
EAAT2, GLT-1 |
| Gene id |
6506 |
| Description of target |
SLC1A2 is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P43004 |
| Protein accession num |
NP_004162 |
| Nucleotide accession num |
NM_004171 |
| Protein size |
574 amino acids |
| Molecular weight |
62kDa |
| Application |
IHC, WB |
| Partner proteins |
MYCN,RELA,SLC1A2,JUB,SLC1A2,JUB |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Uhl,G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693 |
| Description |
This is a synthetic peptide designed for use in combination with anti-SLC1A2 antibody (Catalog #: ARP33840_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
