| Sku |
AAP33489 |
| Old sku |
AAPP04539 |
| Price |
$99.00 |
| Name |
NSD2 Peptide - N-terminal region (AAP33489) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
NSD2 |
| Alias symbols |
WHS, TRX5, KMT3F, KMT3G, MMSET, WHSC1, REIIBP |
| Gene id |
7468 |
| Description of target |
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. |
| Swissprot id |
O96031 |
| Protein accession num |
NP_055734 |
| Nucleotide accession num |
NM_014919 |
| Protein size |
802 amino acids |
| Molecular weight |
88kDa |
| Application |
WB |
| Partner proteins |
HIST1H3A; HIST3H3; HDAC1; TRIM28; UBC; SF3A1; HNRNPR; MPHOSPH10; RAD50; SART3; NUP93; GTF3C4; NOLC1; DDX21; BAZ1B; DDX18; KHSRP; RRP1; SMARCA5; SMC1A; RBM10; XRCC5; VIM; EZR; TOP2B; TOP1; TMPO; SMARCA4; SFPQ; RPN1; RBBP4; RANGAP1; PTBP1; PRKDC; PLRG1; PKP |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Santra,M., et al., (2003) Blood 101 (6), 2374-2376 |
| Description |
This is a synthetic peptide designed for use in combination with anti-WHSC1 antibody (Catalog #: ARP33489_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
