| Sku |
AAP33481 |
| Old sku |
AAPP04531 |
| Price |
$99.00 |
| Name |
NR1H2 Peptide - middle region (AAP33481) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
NR1H2 |
| Alias symbols |
LXR-b, LXRB, NER, NER-I, RIP15, UNR |
| Gene id |
7376 |
| Description of target |
NR1H2 is an orphan receptor. NR1H2 binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4).The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995 [PubMed 7625741]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P55055 |
| Protein accession num |
NP_009052 |
| Nucleotide accession num |
NM_007121 |
| Protein size |
461 amino acids |
| Molecular weight |
51kDa |
| Application |
WB |
| Partner proteins |
FOXO3,ING3,MDFI,MED1,NCOA3,NCOA6,NCOR1,NCOR2,NR0B2,NR1H2,NRIP1,RARA,RXRA,RXRB,RXRG,TMEM161A,UBE2I,VDR,ZXDC,MDFI,NCOA6,NR0B2,RXRA,RXRB,SIRT1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Schmuth,M., (2008) J. Lipid Res. 49 (3), 499-509 |
| Description |
This is a synthetic peptide designed for use in combination with anti-NR1H2 antibody (Catalog #: ARP33481_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
