RORC Peptide (AAP33244)

Data Sheet
 
Sku AAP33244
Old sku AAPS22101
Price $99.00
Name RORC Peptide (AAP33244)
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Size 100 ug
Gene RORC
Alias symbols MGC129539, NR1F3, RORG, RZRG, TOR, RZR-GAMMA
Gene id 6097
Description of target RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
Swissprot id P51449
Protein accession num NP_005051
Nucleotide accession num NM_005060
Protein size 518 amino acids
Molecular weight 58kDa
Application WB
Partner proteins CHD4,EIF4EBP1,NCOA6
Quality control The peptide is characterized by mass spectroscopy
Key reference Wang,H., et al., (2003) Mol. Genet. Metab. 79 (3), 176-182
Description This is a synthetic peptide designed for use in combination with anti-RORC antibody (Catalog #: ARP33244_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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