JMJD2C Peptide - C-terminal region (AAP32974)

Data Sheet
 
Sku AAP32974
Old sku AAPP04002
Price $99.00
Name JMJD2C Peptide - C-terminal region (AAP32974)
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Size 100 ug
Gene KDM4C
Alias symbols FLJ25949, GASC1, JHDM3C, JMJD2C, KIAA0780, bA146B14.1
Gene id 23081
Description of target JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.
Swissprot id F5H347
Protein accession num NP_001140167
Nucleotide accession num NM_001146695
Protein size 1056 amino acids
Molecular weight 120kDa
Application WB
Partner proteins UBC; HIST2H3C; HDAC3; PPARG; HDAC1; H3F3A; HIST1H3A; KDM4C; KDM4A;
Quality control The peptide is characterized by mass spectroscopy
Key reference Katoh,Y. (2007) Int. J. Mol. Med. 20 (2), 269-273
Description This is a synthetic peptide designed for use in combination with anti-JMJD2C antibody (Catalog #: ARP32974_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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