Sku |
AAP32974 |
Old sku |
AAPP04002 |
Price |
$99.00 |
Name |
JMJD2C Peptide - C-terminal region (AAP32974) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
KDM4C |
Alias symbols |
FLJ25949, GASC1, JHDM3C, JMJD2C, KIAA0780, bA146B14.1 |
Gene id |
23081 |
Description of target |
JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. |
Swissprot id |
F5H347 |
Protein accession num |
NP_001140167 |
Nucleotide accession num |
NM_001146695 |
Protein size |
1056 amino acids |
Molecular weight |
120kDa |
Application |
WB |
Partner proteins |
UBC; HIST2H3C; HDAC3; PPARG; HDAC1; H3F3A; HIST1H3A; KDM4C; KDM4A; |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Katoh,Y. (2007) Int. J. Mol. Med. 20 (2), 269-273 |
Description |
This is a synthetic peptide designed for use in combination with anti-JMJD2C antibody (Catalog #: ARP32974_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |