| Sku |
AAP32807 |
| Old sku |
AAPP03826 |
| Price |
$99.00 |
| Name |
PHB Peptide (AAP32807) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
PHB |
| Alias symbols |
PHB1 |
| Gene id |
5245 |
| Description of target |
Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA. |
| Swissprot id |
P35232 |
| Protein accession num |
NP_002625 |
| Nucleotide accession num |
NM_002634 |
| Protein size |
272 amino acids |
| Molecular weight |
30kDa |
| Application |
IHC, WB |
| Partner proteins |
RAF1,SMARCA2,SMARCA4,ANXA2,E2F1,HDAC1,MAP3K10,NCOR1,RAF1,RB1,RBL1,RBL2,SIN3A,SMARCA2,SMARCA4,SUMO4,TP53,XPO1,ACTN1,ANXA2,BRE,E2F1,HDAC1,MYOD1,NCOR1,RAF1,RB1,RBL1,RBL2,SIN3A,SMARCA2,SMARCA4,TP53 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Fraering,P.C., et al., (2004) Biochemistry 43 (30), 9774-9789 |
| Description |
This is a synthetic peptide designed for use in combination with anti-PHB antibody (Catalog #: ARP32807_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
