SUZ12 Peptide (AAP32515)

Data Sheet
 
Sku AAP32515
Old sku AAPP03518
Price $99.00
Name SUZ12 Peptide (AAP32515)
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Size 100 ug
Gene SUZ12
Alias symbols CHET9, JJAZ1, KIAA0160
Gene id 23512
Description of target A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7;17)(p15;q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id Q15022
Protein accession num NP_056170
Nucleotide accession num NM_015355
Protein size 739 amino acids
Molecular weight 83kDa
Application CHIP, IHC, WB
Partner proteins AEBP2,EED,RBBP4,AEBP2,EZH2,AEBP2,CTCF,EED,EZH2,GTF2I,JARID2,MTF2,RBBP4,SETDB1,SNAI1,UBE2I,VAV1,WDR77
Quality control The peptide is characterized by mass spectroscopy
Key reference Li,H., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (50), 20001-20006
Description This is a synthetic peptide designed for use in combination with anti-SUZ12 antibody (Catalog #: ARP32515_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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