| Sku |
AAP32478 |
| Old sku |
AAPP03477 |
| Price |
$99.00 |
| Name |
REST Peptide - middle region (AAP32478) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
REST |
| Alias symbols |
NRSF, XBR |
| Gene id |
5978 |
| Description of target |
REST is a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis.This gene encodes a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described; however, their full length nature has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
Q13127 |
| Protein accession num |
NP_005603 |
| Nucleotide accession num |
NM_005612 |
| Protein size |
1097 amino acids |
| Molecular weight |
122kDa |
| Application |
WB |
| Partner proteins |
CTDSP1,EHMT2,GRM2,STMN2,HTT,RCOR1,SIN3B,HDAC1,HDAC2,Hdac1,KDM5C,NCOR1,RCOR1,RNF2,Sin3a,Sin3b |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Miyajima,F., (er) Genes Brain Behav. (2008) In press |
| Description |
This is a synthetic peptide designed for use in combination with anti-REST antibody (Catalog #: ARP32478_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
