SRC Peptide - N-terminal region (AAP32475)

Data Sheet
 
Sku AAP32475
Old sku AAPP03474
Price $99.00
Name SRC Peptide - N-terminal region (AAP32475)
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Size 100 ug
Gene SRC
Alias symbols ASV, SRC1, c-SRC, p60-Src
Gene id 6714
Description of target This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Swissprot id P12931
Protein accession num NP_938033
Nucleotide accession num NM_198291
Protein size 536 amino acids
Molecular weight 60kDa
Application WB
Partner proteins E2F4,ABL1,BCAR1,BCR,CDCP1,DRD4,ERBB2,ETS1,ETS2,GJA1,GJB1,HNRNPK,KHDRBS1,MUC1,PDE4D,PDGFRB,PTK2,PTK2,PTPN2,RGS16,SHB,SHC1,SRC,ABL1,ACTN1,ADAM12,ADAM15,ADRB2,ADRB3,ADRBK1,AFAP1,AFAP1L2,AKT1,ANKRD11,ANXA1,ANXA2,AR,ARHGAP1,ARHGAP32,ARR3,ASAP1,ATP2B4,AXL,BCAR1,BCR,BMX,CAV1,CAV2,CBL,CBLC,CD2AP,CD33,CD36,CD46,CD59,CDCP1,CDH5,CDK5,CDKN1B,CEACAM1,CEACAM3,CHUK,CNTNAP1,CSK,CTNNB1,CTNND1,CTTN,DAB1,DAB2,DAG1,DAPP1,DDR2,DGKA,DGKZ,DLG4,DNM1,DNM2,DOK1,DOK2,DOK4,EFNB1,EFNB2,EGFR,EPHB2,EPS8,ERBB2,ESR1,ESR2,ETS1,ETS2,EVL,FARP2,FASLG,FGR,FHIT,FOXO1,FRS2,FYB,GAB2,GAB3,GFAP,GIT1,GJA1,GJB1,GNB2L1,GRB10,GRB2,GRIN2A,GRIN2B,GRLF1,GTF2I,GUCY2C,HLA-A,HLA-B,HNF1A,HNRNPK,HRAS,HSP90AA1,IGF1R,IKBKB,IKBKG,IL6R,INPPL1,INSR,ITGB3,JUP,KCNA5,KCNB1,KCNQ5,KDR,KHDRBS1,KIFAP3,KIT,LRP1,MAPK15,MATK,MED28,MET,MPZL1,MST1R,MUC1,MYLK,ND2,NFKBIA,NMT1,NOS2,NPHS1,NR1I2,P2RY2,PAK2,PDCD6IP,PDE6G,PDGFRB,PDPK1,PECAM1,PGR,PIK3R1,PKD1,PLCG1,PPARD,PPP2R4,PRKACA,PRKCA,PRKCD,PRKCE,PRKCH,PRKCI,PRKCZ,PRKD1,PTK2,PTK2B,PTPN1,PTPN11,PTPN18,PTPN2,PTPN21,PTPN6,PTPRA,PTPRE,PXN,RAF1,RASA1,RET,RGS16,RXRA,SH2D3C,SH3BP1,SH3PXD2A,SHB,SHC1,SKAP1,SLC9A2,SMARCB1,SMARCE1,SPTAN1,SRC,SRF,STAP2,STAT1,STAT3,STAT5A,STAT5B,STAT6,SYK,SYN1,TERT,THRA,TIAM1,TNFRSF11A,TRAF1,TRAF3,TRAF6,TRAT1,TRIP10,TRIP6,TRPC6,TRPV4,TUB,TXK,TYRO3,VCL,VIL1,WAS,WBP11,WWOX,YTHDC1,YWHAB,YWHAE,YWHAG,YWHAH,ABL1,ADRB2,ADRB3,ADRBK1,AHR,AR,ARHGAP1,ARHGAP17,ARHGAP32,ARHGAP32,ARNT,ARR3,ASAP1,ASAP2,AXL,Adrb3,BCAR1,BMX,CAV1,CAV2,CBL,CD44,CD46,CDC25C,CDC37,CDH1,CRK,CSF1R,CSK,CTNND1,DAB2,DAG1,DDR2,DOCK1,DOK1,DOK4,EFNB1,EGFR,EP300,EPHA3,EPHA4,EPHB2,EPS8,ERBB2,ESR1,ESR2,EVL,FOXO1,FYN,GAB2,GAB3,GNB2L1,GRB10,GRB2,GRIN2A,GSN,HNF1A,HSP90AA1,ITK,KHDRBS1,KIFAP3,LRP1,LYN,MAP2,MAPK8IP3,MATK,MET,MICAL1,MPZL1,MUC1,MYLK,NCOA6,ND2,PDE6G,PECAM1,PELP1,PIK3R1,PLCG1,PLD1,PLD2,PLSCR1,PRKCZ,PTK2,PTK2B,PTPN21,PTPRA,PXN,RAF1,RARA,RASA1,RET,RPL10,RPS6KB1,RPS6KB2,RXRA,SH3BP1,SHB,SKAP1,SLC9A2,SNURF,SRF,STAT1,STAT3,SYK,SYN1,THRB,TNFSF11,TRAF1,TRAF3,TRAF6,TRIP4,TRIP6,TRPC6,TRPV4,TYRO3,WAS
Quality control The peptide is characterized by mass spectroscopy
Key reference Pechkovsky,D.V., (2008) J. Biol. Chem. 283 (19), 12898-12908
Description This is a synthetic peptide designed for use in combination with anti-SRC antibody (Catalog #: ARP32475_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
Protocol
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