| Sku |
AAP32355 |
| Old sku |
AAPP03344 |
| Price |
$99.00 |
| Name |
ASCL1 Peptide (AAP32355) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
ASCL1 |
| Alias symbols |
ASH1, HASH1, MASH1, bHLHa46 |
| Gene id |
429 |
| Description of target |
ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. |
| Swissprot id |
P50553 |
| Protein accession num |
NP_004307 |
| Nucleotide accession num |
NM_004316 |
| Protein size |
236 amino acids |
| Molecular weight |
25kDa |
| Application |
IHC, WB |
| Partner proteins |
ASCL1,BMP2,EP300,MEF2A,NEUROG2,TCF4,UBQLN1,EP300,MEF2A,TCF4 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Somasundaram,K., et al., (2005) Oncogene. 24(47), 7073-83 |
| Description |
This is a synthetic peptide designed for use in combination with anti-ASCL1 antibody (Catalog #: ARP32355_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
