BMP7 Peptide (AAP32329)

Data Sheet
 
Sku AAP32329
Old sku AAPP03316
Price $99.00
Name BMP7 Peptide (AAP32329)
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Size 100 ug
Gene BMP7
Alias symbols OP-1
Gene id 655
Description of target The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
Swissprot id P18075
Protein accession num NP_001710
Nucleotide accession num NM_001719
Protein size 431 amino acids
Molecular weight 49kDa
Application IHC, WB
Partner proteins ACVR1,ACVR2A,ACVR2B,BMPR1A,BMPR1B,BMPR2,CHRDL2,ENG,GDF7,NCOA3,NOG,SOSTDC1,ACVR1,ACVR2A,ACVR2B,BMP7,BMPR1A,BMPR1B,BMPR2,ENG,NOG,SMAD1,SMAD3,SOSTDC1
Quality control The peptide is characterized by mass spectroscopy
Key reference Gregory,K.E., (2005) J. Biol. Chem. 280 (30), 27970-27980
Description This is a synthetic peptide designed for use in combination with anti-BMP7 antibody (Catalog #: ARP32329_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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