IRF6 Peptide - middle region (AAP31995)

Data Sheet
 
Sku AAP31995
Old sku AAPP02892
Price $99.00
Name IRF6 Peptide - middle region (AAP31995)
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Size 100 ug
Gene IRF6
Alias symbols LPS, OFC6, PIT, PPS, VWS, VWS1
Gene id 3664
Description of target IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id O14896
Protein accession num NP_006138
Nucleotide accession num NM_006147
Protein size 467 amino acids
Molecular weight 53kDa
Application IHC, WB
Partner proteins LBP
Quality control The peptide is characterized by mass spectroscopy
Key reference Vieira,A.R., (er) Arch. Oral Biol. (2008) In press
Description This is a synthetic peptide designed for use in combination with anti-IRF6 antibody (Catalog #: ARP31995_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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