Sku |
AAP31992 |
Old sku |
AAPP23941 |
Price |
$99.00 |
Name |
IRF3 Peptide (AAP31992) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
IRF3 |
Gene id |
3661 |
Description of target |
IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. |
Swissprot id |
Q14653 |
Protein accession num |
NP_001562 |
Nucleotide accession num |
NM_001571 |
Protein size |
427 amino acids |
Molecular weight |
47kDa |
Application |
WB |
Partner proteins |
CDKL2,CREBBP,CXCL10,E6,IRF3,CREBBP,EP300,GRIP1,IKBKE,IRF3,IRF5,IRF7,MAVS,PIAS4,PPIB,PRDX1,RELA,SERPINB2,SMURF2,SYT1,TBK1,TICAM1,TICAM2,CREBBP,DDX58,IKBKE,IRF5,IRF7,PPIP5K1,PRDX1,TANK,TBK1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Korherr,C., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (11), 4240-4245 |
Description |
This is a synthetic peptide designed for use in combination with anti-IRF3 antibody (Catalog #: ARP31992_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |