Sku |
AAP31737 |
Old sku |
AAPP02528 |
Price |
$99.00 |
Name |
SOX2 Peptide - N-terminal region (AAP31737) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
SOX2 |
Alias symbols |
ANOP3, MCOPS3, MGC2413 |
Gene id |
6657 |
Description of target |
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P48431 |
Protein accession num |
NP_003097 |
Nucleotide accession num |
NM_003106 |
Protein size |
317 amino acids |
Molecular weight |
34kDa |
Application |
IHC, WB |
Partner proteins |
NR5A1,POU2F1,POU5F1,PAX6,POU5F1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Wang,P., (2008) Arch. Ophthalmol. 126 (5), 709-713 |
Description |
This is a synthetic peptide designed for use in combination with anti-SOX2 antibody (Catalog #: ARP31737_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |