SOX2 Peptide - N-terminal region (AAP31737)

Data Sheet
 
Sku AAP31737
Old sku AAPP02528
Price $99.00
Name SOX2 Peptide - N-terminal region (AAP31737)
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Size 100 ug
Gene SOX2
Alias symbols ANOP3, MCOPS3, MGC2413
Gene id 6657
Description of target SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id P48431
Protein accession num NP_003097
Nucleotide accession num NM_003106
Protein size 317 amino acids
Molecular weight 34kDa
Application IHC, WB
Partner proteins NR5A1,POU2F1,POU5F1,PAX6,POU5F1
Quality control The peptide is characterized by mass spectroscopy
Key reference Wang,P., (2008) Arch. Ophthalmol. 126 (5), 709-713
Description This is a synthetic peptide designed for use in combination with anti-SOX2 antibody (Catalog #: ARP31737_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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