RIPK3 Peptide (AAP31513)

Data Sheet
 
Sku AAP31513
Old sku AAPP24084
Price $99.00
Name RIPK3 Peptide (AAP31513)
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Size 100 ug
Gene RIPK3
Alias symbols RIP3, RIP3 beta, RIP3 gamma
Gene id 11035
Description of target RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Swissprot id Q9Y572
Protein accession num NP_006862
Nucleotide accession num NM_006871
Protein size 518 amino acids
Molecular weight 57kDa
Application IHC, WB
Partner proteins RIPK1,TICAM1,TNFRSF1A,TRAF2,RIPK1,TICAM1,TNFRSF1A,TRAF2
Quality control The peptide is characterized by mass spectroscopy
Key reference Kimura,K., (2006) Genome Res. 16 (1), 55-65
Description This is a synthetic peptide designed for use in combination with anti-RIPK3 antibody (Catalog #: ARP31513_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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