HOXA5 Peptide - middle region (AAP31447)

Data Sheet
 
Sku AAP31447
Old sku AAPP02209
Price $99.00
Name HOXA5 Peptide - middle region (AAP31447)
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Size 100 ug
Gene HOXA5
Alias symbols HOX1, HOX1.3, HOX1C, MGC9376
Gene id 3202
Description of target In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id Q6FG31
Protein accession num NP_061975
Nucleotide accession num NM_019102
Protein size 270 amino acids
Molecular weight 29kDa
Application IHC, WB
Partner proteins TWIST1,CDX4,FOXA2,FOXO1,MEIS1,PBX1,TWIST1,FOXA2,FOXO1
Quality control The peptide is characterized by mass spectroscopy
Key reference Chen,Y. (2008) Blood 111 (3), 1217-1226
Description This is a synthetic peptide designed for use in combination with anti-HOXA5 antibody (Catalog #: ARP31447_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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