Sku |
AAP31447 |
Old sku |
AAPP02209 |
Price |
$99.00 |
Name |
HOXA5 Peptide - middle region (AAP31447) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
HOXA5 |
Alias symbols |
HOX1, HOX1.3, HOX1C, MGC9376 |
Gene id |
3202 |
Description of target |
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
Q6FG31 |
Protein accession num |
NP_061975 |
Nucleotide accession num |
NM_019102 |
Protein size |
270 amino acids |
Molecular weight |
29kDa |
Application |
IHC, WB |
Partner proteins |
TWIST1,CDX4,FOXA2,FOXO1,MEIS1,PBX1,TWIST1,FOXA2,FOXO1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Chen,Y. (2008) Blood 111 (3), 1217-1226 |
Description |
This is a synthetic peptide designed for use in combination with anti-HOXA5 antibody (Catalog #: ARP31447_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
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Tips |
See our General FAQ page. |
Availability |
In Stock |