POU1F1 Peptide (AAP31419)

Data Sheet
 
Sku AAP31419
Old sku AAPP03105
Price $99.00
Name POU1F1 Peptide (AAP31419)
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Size 100 ug
Gene POU1F1
Alias symbols PIT1, CPHD1, GHF-1, Pit-1, POU1F1a
Gene id 5449
Description of target PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
Swissprot id P28069
Protein accession num NP_000297
Nucleotide accession num NM_000306
Protein size 291 amino acids
Molecular weight 33kDa
Application IHC, WB
Partner proteins CREBBP,ETS1,GATA2,JUN,NR1I2,NR1I3,NR3C1,PITX1,GATA2,JUN,NR1I2,NR1I3,NR3C1,PITX1,PPARA,PPARG,VDR
Quality control The peptide is characterized by mass spectroscopy
Key reference Dattani,M.T., et al., (2003) GrowthHorm.IGFRes.16(9),1207-1209
Description This is a synthetic peptide designed for use in combination with anti-POU1F1 antibody (Catalog #: ARP31419_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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