| Sku |
AAP31326 |
| Old sku |
AAPP02076 |
| Price |
$99.00 |
| Name |
TAF12 Peptide - N-terminal region (AAP31326) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
TAF12 |
| Alias symbols |
TAF2J, TAFII20 |
| Gene id |
6883 |
| Description of target |
Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I.Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
Q16514 |
| Protein accession num |
NP_005635 |
| Nucleotide accession num |
NM_005644 |
| Protein size |
161 amino acids |
| Molecular weight |
18kDa |
| Application |
WB, CHIP |
| Partner proteins |
ATF7,TAF4B,ATF7,CPSF1,TAF1,TAF10,TAF11,TAF15,TAF2,TAF4,TAF5,TAF6,TAF7,TAF8,TAF9,TBP,ATXN7,MYC,SUPT3H,TAF4,TAF5,TAF6,TAF9 |
| Subunit |
12 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Denissov,S., (2007) EMBO J. 26 (4), 944-954 |
| Description |
This is a synthetic peptide designed for use in combination with anti-TAF12 antibody (Catalog #: P100965_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
