| Sku |
AAP31308 |
| Old sku |
AAPP02058 |
| Price |
$99.00 |
| Name |
MAX Peptide - N-terminal region (AAP31308) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
MAX |
| Alias symbols |
MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, orf1, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8 |
| Gene id |
4149 |
| Description of target |
MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown. The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown. |
| Swissprot id |
P61244 |
| Protein accession num |
NP_660087 |
| Nucleotide accession num |
NM_145112 |
| Protein size |
151 amino acids |
| Molecular weight |
17kDa |
| Application |
WB |
| Partner proteins |
MSH2,MXD1,MXI1,MYC,CASP5,CASP7,CSNK2A1,EPAS1,HIF1A,MAD1L1,MAPK14,MAX,MNT,MSH2,MXD1,MXD3,MXD4,MYC,MYCL1,MYCN,PLEKHF2,SMAD3,SMAD4,SNIP1,SPAG9,TEAD1,TRRAP,EP400,KAT2A,KDM5C,MAD1L1,MAX,MNT,MSH2,MXD1,MXD3,MXD4,MXI1,MYC,MYCL1,MYCN,PLEKHF2,SMAD3,SMAD4,SPAG9,TEAD1,TRRAP,ZBTB17 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Faiola,F., (2007) Biochem. J. 403 (3), 397-407 |
| Description |
This is a synthetic peptide designed for use in combination with anti-MAX antibody (Catalog #: P100953_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
