CEBPA Peptide (AAP31256)

Data Sheet
 
Sku AAP31256
Old sku AAPP02005
Price $99.00
Name CEBPA Peptide (AAP31256)
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Size 100 ug
Gene CEBPA
Alias symbols CEBP, C/EBP-alpha
Gene id 1050
Description of target CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Swissprot id P49715
Protein accession num NP_004355
Nucleotide accession num NM_004364
Protein size 358 amino acids
Molecular weight 38kDa
Application WB
Partner proteins LTF,NCOA6,PIAS1,ATF2,CDK2,CDK4,CDKN1A,CDKN3,CDX1,CEBPA,CEBPB,CEBPD,CREBBP,CTNNB1,DBP,EP300,GATA2,GSK3B,HNF1A,MSX2,MYC,NCOA6,NFYA,NR3C1,PIAS1,RB1,RBL1,RFC1,RUNX1,SOX10,SOX8,SPI1,SUMO3,AR,ATF2,Atf2,CDK2,CDK4,CEBPB,CTNNB1,ESR1,MAPK8,MSX2,MYC,NCOA6,NR3C1,RARB,SMAD3,SMAD4,SPI1,UBC
Quality control The peptide is characterized by mass spectroscopy
Key reference Zhu,Q.S., et al., (2004) J. Biol. Chem. 279 (29), 29902-29910
Description This is a synthetic peptide designed for use in combination with anti-CEBPA antibody (Catalog #: P100908_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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