| Sku |
AAP31240 |
| Old sku |
AAPP01985 |
| Price |
$99.00 |
| Name |
GTF2E1 Peptide (AAP31240) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
GTF2E1 |
| Alias symbols |
FE, TF2E1, TFIIE-A |
| Gene id |
2960 |
| Description of target |
The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57,000 (TFIIE-alpha) and 34,000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation |
| Swissprot id |
P29083 |
| Protein accession num |
NP_005504 |
| Nucleotide accession num |
NM_005513 |
| Protein size |
439 amino acids |
| Molecular weight |
49kDa |
| Application |
IHC, WB |
| Partner proteins |
AES,ERCC3,GTF2A1,GTF2A2,GTF2B,GTF2E2,GTF2F2,GTF2H1,GTF2H4,SND1,TAF6,TBP,TCEA1,TRIM24,AES,BRCA1,ERCC3,GTF2A1,GTF2B,GTF2E2,GTF2F1,GTF2F2,GTF2H4,MDM2,MED21,POLR2A,SND1,TAF1,TAF11,TAF6,TBP,TCEA1,TRIM24 |
| Subunit |
1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Ohkuma,Y., et al., (1991) Nature 354 (6352), 398-401 |
| Description |
This is a synthetic peptide designed for use in combination with anti-GTF2E1 antibody (Catalog #: P100892_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
