Sku |
AAP31236 |
Old sku |
AAPP01981 |
Price |
$99.00 |
Name |
LEF1 Peptide - N-terminal region (AAP31236) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
LEF1 |
Alias symbols |
DKFZp586H0919, TCF1ALPHA, LEF-1, TCF10, TCF7L3 |
Gene id |
51176 |
Description of target |
Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1). Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA; MIM 186880) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1; MIM 163905).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
Q9UJU2 |
Protein accession num |
NP_057353 |
Nucleotide accession num |
NM_016269 |
Protein size |
399 amino acids |
Molecular weight |
44kDa |
Application |
WB |
Partner proteins |
CTNNB1,SMAD3,TLE1,ALX4,CDX1,CTNNB1,EP300,KPNA1,KPNA2,MITF,NLK,NOTCH1,PIAS4,PITX2,RUNX2,SMAD1,SMAD2,SMAD3,SMAD4,SUMO2,THOC4,TLE1,UBTF,ALX4,CTNNB1,EP300,Kpna1,Kpna2,MITF,NLK,NOTCH1,PIAS4,RUNX1,RUNX2,RUVBL1,SMAD2,SMAD3,SMAD4,SMAD7,THOC4,TLE1,UBTF |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Petropoulos,K., (2008) J. Exp. Med. 205 (3), 515-522 |
Description |
This is a synthetic peptide designed for use in combination with anti-LEF1 antibody (Catalog #: P100889_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |