POU3F2 Peptide (AAP31219)

Data Sheet
 
Sku AAP31219
Old sku AAPP01964
Price $99.00
Name POU3F2 Peptide (AAP31219)
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Size 100 ug
Gene POU3F2
Alias symbols BRN2, OCT7, OTF7, OTF-7, POUF3, brn-2, oct-7
Gene id 5454
Description of target N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].
Swissprot id P20265
Protein accession num NP_005595
Nucleotide accession num NM_005604
Protein size 443 amino acids
Molecular weight 47kDa
Application WB
Partner proteins EP300,GTF2B,PAX3,POU3F2,SOX10,TBP,EP300,GTF2B,POU3F2,POU3F4,PQBP1,SOX10,SOX11,TBP,POU3F4,PQBP1
Quality control The peptide is characterized by mass spectroscopy
Key reference Goodall,J., (2004) Mol. Cell. Biol. 24 (7), 2923-2931
Description This is a synthetic peptide designed for use in combination with anti-POU3F2 antibody (Catalog #: P100858_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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