Sku |
AAP31219 |
Old sku |
AAPP01964 |
Price |
$99.00 |
Name |
POU3F2 Peptide (AAP31219) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
POU3F2 |
Alias symbols |
BRN2, OCT7, OTF7, OTF-7, POUF3, brn-2, oct-7 |
Gene id |
5454 |
Description of target |
N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM]. |
Swissprot id |
P20265 |
Protein accession num |
NP_005595 |
Nucleotide accession num |
NM_005604 |
Protein size |
443 amino acids |
Molecular weight |
47kDa |
Application |
WB |
Partner proteins |
EP300,GTF2B,PAX3,POU3F2,SOX10,TBP,EP300,GTF2B,POU3F2,POU3F4,PQBP1,SOX10,SOX11,TBP,POU3F4,PQBP1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Goodall,J., (2004) Mol. Cell. Biol. 24 (7), 2923-2931 |
Description |
This is a synthetic peptide designed for use in combination with anti-POU3F2 antibody (Catalog #: P100858_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |