Sku |
AAP31199 |
Old sku |
AAPP01942 |
Price |
$99.00 |
Name |
IRF8 Peptide - middle region (AAP31199) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
IRF8 |
Alias symbols |
H-ICSBP, ICSBP, ICSBP1, IRF-8 |
Gene id |
3394 |
Description of target |
Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection. |
Swissprot id |
Q02556 |
Protein accession num |
NP_002154 |
Nucleotide accession num |
NM_002163 |
Protein size |
426 amino acids |
Molecular weight |
48kDa |
Application |
WB |
Partner proteins |
COPS2,IRF1,IRF2,SMURF2,SPI1,TRAF6,ZBTB17,COPS2,ETV6,IRF1,IRF2,IRF8,NFKB1,RELA,TRIM21,UBC |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Jayakumar,A., (2008) Infect. Immun. 76 (5), 2138-2148 |
Description |
This is a synthetic peptide designed for use in combination with anti-IRF8 antibody (Catalog #: P100842_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |