IRF8 Peptide (AAP31198)

Data Sheet
 
Sku AAP31198
Old sku AAPP01941
Price $99.00
Name IRF8 Peptide (AAP31198)
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Size 100 ug
Gene IRF8
Alias symbols ICSBP, IRF-8, ICSBP1, H-ICSBP
Gene id 3394
Description of target Interferon consensus sequence-binding protein (Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Swissprot id Q02556
Protein accession num NP_002154
Nucleotide accession num NM_002163
Protein size 426 amino acids
Molecular weight 48kDa
Application IHC, WB
Partner proteins COPS2,IRF1,IRF2,SMURF2,SPI1,TRAF6,ZBTB17,COPS2,ETV6,IRF1,IRF2,IRF8,NFKB1,RELA,TRIM21,UBC
Quality control The peptide is characterized by mass spectroscopy
Key reference Weisz,A., et al., (1992) J. Biol. Chem. 267 (35), 25589-25596
Description This is a synthetic peptide designed for use in combination with anti-IRF8 antibody (Catalog #: P100841_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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