Sku |
AAP31162 |
Old sku |
AAPP01905 |
Price |
$99.00 |
Name |
NR2F2 Peptide (AAP31162) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
NR2F2 |
Alias symbols |
ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2, NF-E3, NR2F1, COUPTFII |
Gene id |
7026 |
Description of target |
NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation. |
Swissprot id |
P24468 |
Protein accession num |
NP_066285 |
Nucleotide accession num |
NM_021005 |
Protein size |
414 amino acids |
Molecular weight |
45kDa |
Application |
WB |
Partner proteins |
BCL11A,BCL11B,EP300,FAM46A,HDAC1,HIPK3,MYOD1,NCOR2,NR2F6,NR3C1,PIAS1,SQSTM1,TRIM24,HDAC1,LCK,MYOD1,NR2F6 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Schafer,G., (2008) Cancer Res. 68 (2), 457-466 |
Description |
This is a synthetic peptide designed for use in combination with anti-NR2F2 antibody (Catalog #: P100815_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
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Tips |
See our General FAQ page. |
Availability |
In Stock |