NR2F2 Peptide (AAP31162)

Data Sheet
 
Sku AAP31162
Old sku AAPP01905
Price $99.00
Name NR2F2 Peptide (AAP31162)
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Size 100 ug
Gene NR2F2
Alias symbols ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2, NF-E3, NR2F1, COUPTFII
Gene id 7026
Description of target NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.
Swissprot id P24468
Protein accession num NP_066285
Nucleotide accession num NM_021005
Protein size 414 amino acids
Molecular weight 45kDa
Application WB
Partner proteins BCL11A,BCL11B,EP300,FAM46A,HDAC1,HIPK3,MYOD1,NCOR2,NR2F6,NR3C1,PIAS1,SQSTM1,TRIM24,HDAC1,LCK,MYOD1,NR2F6
Quality control The peptide is characterized by mass spectroscopy
Key reference Schafer,G., (2008) Cancer Res. 68 (2), 457-466
Description This is a synthetic peptide designed for use in combination with anti-NR2F2 antibody (Catalog #: P100815_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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