| Sku |
AAP31161 |
| Old sku |
AAPP01904 |
| Price |
$99.00 |
| Name |
TFAP2A Peptide (AAP31161) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
TFAP2A |
| Alias symbols |
AP-2, BOFS, AP2TF, TFAP2, AP-2alpha |
| Gene id |
7020 |
| Description of target |
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM]. |
| Swissprot id |
P05549 |
| Protein accession num |
NP_003211 |
| Nucleotide accession num |
NM_003220 |
| Protein size |
437 amino acids |
| Molecular weight |
48kDa |
| Application |
WB |
| Partner proteins |
TP53,APC,CASP1,CASP3,CASP6,CITED2,CITED4,CLTC,CTNNB1,DEK,EP300,EPN2,HIP1,LDLRAP1,MAGI1,NPM1,RB1,SUMO4,SYT1,TP53,WWP1,WWP2,YBX1,APC,CITED2,CITED4,CTNNB1,DEK,EP300,GRB2,MYC,TP53,YBX1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Li,M., et al., (2006) Int. J. Cancer 118 (4), 802-811 |
| Description |
This is a synthetic peptide designed for use in combination with anti-TFAP2A antibody (Catalog #: P100878_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
