TFAP2A Peptide (AAP31161)

Data Sheet
Sku AAP31161
Old sku AAPP01904
Price $99.00
Name TFAP2A Peptide (AAP31161)
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Size 100 ug
Alias symbols AP-2, BOFS, AP2TF, TFAP2, AP-2alpha
Gene id 7020
Description of target TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM].
Swissprot id P05549
Protein accession num NP_003211
Nucleotide accession num NM_003220
Protein size 437 amino acids
Molecular weight 48kDa
Application WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Li,M., et al., (2006) Int. J. Cancer 118 (4), 802-811
Description This is a synthetic peptide designed for use in combination with anti-TFAP2A antibody (Catalog #: P100878_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days

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