Sku |
AAP31148 |
Old sku |
AAPP01887 |
Price |
$99.00 |
Name |
ETV6 Peptide - N-terminal region (AAP31148) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
ETV6 |
Alias symbols |
TEL, TEL/ABL |
Gene id |
2120 |
Description of target |
ETV6 (ETS-related protein Tel1, ETS translocation variant 6 , Tel) is an ETS family transcription factor. it contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P41212 |
Protein accession num |
NP_001978 |
Nucleotide accession num |
NM_001987 |
Protein size |
452 amino acids |
Molecular weight |
53kDa |
Application |
WB |
Partner proteins |
ETV6,FLI1,HDAC9,KAT5,L3MBTL,SIN3A,SMURF1,SUMO1,UBE2I,ACTA1,CRKL,ETV6,FBXL6,FLI1,GAB2,GRB2,HDAC9,IRF8,KAT5,L3MBTL,SKP1,UBC |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Rubnitz,J.E., (2008) J. Clin. Oncol. 26 (13), 2186-2191 |
Description |
This is a synthetic peptide designed for use in combination with anti-ETV6 antibody (Catalog #: P100806_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |