| Sku |
AAP31109 |
| Old sku |
AAPP01848 |
| Price |
$99.00 |
| Name |
NFATC1 Peptide - N-terminal region (AAP31109) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
NFATC1 |
| Alias symbols |
MGC138448, NF-ATC, NFAT2, NFATc |
| Gene id |
4772 |
| Description of target |
NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes. The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. |
| Swissprot id |
O95644-2 |
| Protein accession num |
NP_765978 |
| Nucleotide accession num |
NM_172390 |
| Protein size |
716 amino acids |
| Molecular weight |
78kDa |
| Application |
WB |
| Partner proteins |
EP300,GNB2L1,MAPK14,PIM1,PPP3R1,PRKCA,SPI1,EGR1,EGR2,PIM1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Crotti,T.N., (2008) J. Cell. Physiol. 215 (3), 636-644 |
| Description |
This is a synthetic peptide designed for use in combination with anti-NFATC1 antibody (Catalog #: P100981_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
