Sku |
AAP31077 |
Old sku |
AAPP01816 |
Price |
$99.00 |
Name |
REL Peptide - N-terminal region (AAP31077) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
REL |
Alias symbols |
C-Rel |
Gene id |
5966 |
Description of target |
REL is a member of the Rel/NFKB family, which also includes RELA, RELB, NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor.The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-174 CN414487.1 2-175 175-2323 X75042.1 128-2276 2324-2457 BX111941.1 575-708 2458-2592 AA279919.1 1-135 c |
Swissprot id |
Q04864 |
Protein accession num |
NP_002899 |
Nucleotide accession num |
NM_002908 |
Protein size |
619 amino acids |
Molecular weight |
68kDa |
Application |
WB |
Partner proteins |
CALM1,CCNE1,ELF1,GTF2B,HSPA8,MAP3K8,MAPK8,NFKB1,NFKB2,NFKBIA,NFKBIB,NFKBIE,NKRF,NOTCH1,PPP4C,REL,RELA,SP1,TBP,TNIP2,CDK2,ELF1,GTF2B,MAP3K8,MAPK8,MTPN,NFKB1,NFKB2,NFKBIA,NFKBIB,NFKBIE,NKRF,Nfkb1,PAPOLA,PPP4C,RELA,SP1,SRF,TBK1,TBP,TNIP2 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Kerppola,T.K. (er) Ann. Rheum. Dis. (2008) In press |
Description |
This is a synthetic peptide designed for use in combination with anti-REL antibody (Catalog #: P100756_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |