REL Peptide - N-terminal region (AAP31077)

Data Sheet
 
Sku AAP31077
Old sku AAPP01816
Price $99.00
Name REL Peptide - N-terminal region (AAP31077)
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Size 100 ug
Gene REL
Alias symbols C-Rel
Gene id 5966
Description of target REL is a member of the Rel/NFKB family, which also includes RELA, RELB, NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor.The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-174 CN414487.1 2-175 175-2323 X75042.1 128-2276 2324-2457 BX111941.1 575-708 2458-2592 AA279919.1 1-135 c
Swissprot id Q04864
Protein accession num NP_002899
Nucleotide accession num NM_002908
Protein size 619 amino acids
Molecular weight 68kDa
Application WB
Partner proteins CALM1,CCNE1,ELF1,GTF2B,HSPA8,MAP3K8,MAPK8,NFKB1,NFKB2,NFKBIA,NFKBIB,NFKBIE,NKRF,NOTCH1,PPP4C,REL,RELA,SP1,TBP,TNIP2,CDK2,ELF1,GTF2B,MAP3K8,MAPK8,MTPN,NFKB1,NFKB2,NFKBIA,NFKBIB,NFKBIE,NKRF,Nfkb1,PAPOLA,PPP4C,RELA,SP1,SRF,TBK1,TBP,TNIP2
Quality control The peptide is characterized by mass spectroscopy
Key reference Kerppola,T.K. (er) Ann. Rheum. Dis. (2008) In press
Description This is a synthetic peptide designed for use in combination with anti-REL antibody (Catalog #: P100756_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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